Genome Screen for QTLs Contributing to Normal Variation in Bone Mineral Density and Osteoporosis*
نویسندگان
چکیده
منابع مشابه
Low bone mineral density and osteoporosis in CF
Throughout life the skeleton is constantly remodelled by a co-ordinated programme of cellular activity that removes, renews and repairs damaged bone. About 10% of the adult skeleton is remodelled each year. Specialised cells, perhaps stimulated by factors released when bone undergoes even microscopic damage, resorb a specific amount of bone from the damaged areas before undergoing a programmed ...
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Background: The Singh index is an inexpensive simple method to evaluate bone density, commonly used to assess osteoporosis is based on the radiological appearance of the trabecular bone structure of the proximal femur on a plain antero-posterior (AP) radiograph. The purpose of this study was to compare between Singh index and bone mineral density measurement using dual energy X-ray abs...
متن کاملBone mineral density, osteoporosis, and osteoporotic fractures: a genome-wide association study
BACKGROUND Osteoporosis is diagnosed by the measurement of bone mineral density, which is a highly heritable and multifactorial trait. We aimed to identify genetic loci that are associated with bone mineral density. METHODS In this genome-wide association study, we identified the most promising of 314 075 single nucleotide polymorphisms (SNPs) in 2094 women in a UK study. We then tested these...
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Background: Iron overload influences negatively on bone mineral density (BMD) but the results of studies regarding serum ferritin (SF) and BMD are conflicting.This study aimed to determine the association of SF and BMD in the elderly. Methods: All participants of the Amirkola cohort selected between 2011-2012, aged > 60 years were classified as high or normal (<200ng/ml) SF. BMD at femoral nec...
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ژورنال
عنوان ژورنال: The Journal of Clinical Endocrinology & Metabolism
سال: 2000
ISSN: 0021-972X,1945-7197
DOI: 10.1210/jcem.85.9.6778